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Tafamidis meglumine
- Fx-1006A
Axon 4021
- Parent CAS: 594839-88-0
Purity:
99%
- Soluble in 0.1N NaOH(aq) and DMSO
- MF: C14H7Cl2NO3.C7H17NO5
- MW: 503.33
Description
Tafamids meglumine is a small-molecule inhibitor that binds selectively to the transthyretin (TTR) protein in human plasma and kinetically stabilizes the tetrameric structure of both wild-type TTR and a number of different mutants. Tafamidis is an oral medication for treating cardiomyopathy and peripheral neuropathy due to transthyretin amyloidosis (ATTR). It is a transthyretin stabilizer and has been shown to reduce disease progression and mortality significantly.
More Information
| Parent CAS No. | 594839-88-0 |
|---|---|
| Chemical Name | (2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentaol 2-(3,5-dichlorophenyl)benzo[d]oxazole-6-carboxylate |
| MFCD | MFCD28502032 |
| Short Description | Selective TTR stabilizer |
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