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Harmine
Axon 3627
CAS:
442-51-3
Purity:
99%
- Soluble in 0.1N HCl(aq), DMSO and EtOH
- MF: C13H12N2O
- MW: 212.25
Description
Harmine is a potent, selective and ATP-competitive DYRK1A inhibitor with IC50 values of 33 nM, 166 nM, 1.9 μM, and 80 μM for DYRK1A, DYRK1B, DYRK2, and DYRK4, respectively. Harmine has many pharmacological activities including anti-inflammatory, neuroprotective, antidiabetic, and antitumor activities.
More Information
| Parent CAS No. | 442-51-3 |
|---|---|
| Chemical Name | 7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole |
| SMILES | C12C=CN=C(C)C=1NC1C=C(OC)C=CC2=1 |
| MFCD | MFCD00004958 |
| InChi | InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3 |
| InChiKey | BXNJHAXVSOCGBA-UHFFFAOYSA-N |
| CID | 5280953 |
| Short Description | DYRK1A inhibitor |
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