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GSK2795039
Axon 3526
CAS:
1415925-18-6
Purity:
99%
- Soluble in 0.1N NaOH(aq), DMSO and EtOH
- MF: C23H26N6O2S
- MW: 450.56
Description
GSK2795039 is a potent and selective NADPH oxidase 2 (NOX2) inhibitor. GSK2795039 inhibited both the formation of ROS and the utilization of the enzyme substrates, NADPH and oxygen, in a variety of semirecombinant cell-free (with pIC50 values in the range of 6.18 to 6.60) and cell-based NOX2 assays.
More Information
| Parent CAS No. | 1415925-18-6 |
|---|---|
| Chemical Name | N-(1-Isopropyl-3-(1-methylindolin-6-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-methyl-1H-pyrazole-3-sulfonamide |
| MFCD | N.A. |
| Short Description | NOX2 inhibitor |
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