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VCP171
Axon 3519
CAS:
1018830-99-3
Purity:
99%
- Soluble in DMSO and EtOH
- MF: C18H12F3NOS
- MW: 347.35
Description
VCP171 is a positive allosteric modulator (PAM) of adenosine A1 receptors (pKB = 5.65). Reducing AMPA receptor-mediated evoked excitatory postsyneaptic currents (eEPSCs) in lamina I and lamina II neurons in a rat model of neuropathic pains.
More Information
| Parent CAS No. | 1018830-99-3 |
|---|---|
| Chemical Name | (2-Amino-4-(3-(trifluoromethyl)phenyl)thiophen-3-yl)(phenyl)methanone |
| SMILES | C1(C(F)(F)F)C=C(C2=CSC(N)=C2C(C2=CC=CC=C2)=O)C=CC=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C18H12F3NOS/c19-18(20,21)13-8-4-7-12(9-13)14-10-24-17(22)15(14)16(23)11-5-2-1-3-6-11/h1-10H,22H2 |
| InChiKey | HNHLVOBHWXLIGP-UHFFFAOYSA-N |
| CID | 24873485 |
| Short Description | PAM of A1 receptor |
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