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PF-8380
Axon 3442
CAS:
1144035-53-9
Purity:
98%
- Soluble in DMSO
- MF: C22H21Cl2N3O5
- MW: 478.33
Description
PF-8380 is a potent, orally bioavailable autotaxin inhibitor with IC50 values of 2.8 nM and 101 nM in isolated enzyme assay and human whole blood, respectively.
More Information
| Parent CAS No. | 1144035-53-9 |
|---|---|
| Chemical Name | 3,5-Dichlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate |
| SMILES | C1C=C2NC(=O)OC2=CC=1C(CCN1CCN(C(OCC2C=C(Cl)C=C(Cl)C=2)=O)CC1)=O |
| MFCD | N.A. |
| InChi | InChI=1S/C22H21Cl2N3O5/c23-16-9-14(10-17(24)12-16)13-31-22(30)27-7-5-26(6-8-27)4-3-19(28)15-1-2-18-20(11-15)32-21(29)25-18/h1-2,9-12H,3-8,13H2,(H,25,29) |
| InChiKey | JMSUDQYHPSNBSN-UHFFFAOYSA-N |
| CID | 25265312 |
| Short Description | ATX inhibitor |
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