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PD-1 inhibitor compound 9
Axon 2875
- Parent CAS: 1956324-49-4
Purity:
98%
- Soluble in water and DMSO
- MF: C13H19N3O5.HCl
- MW: 333.77
Description
Inhibitor of the programmed death-1 (PD-1) protein. PD-1 inhibitor compound 9 blocked the interaction between PD-1 and its ligand PD-L1 with an inhibitory percentage of 43.0% at a concentration of 500 μM.
More Information
| Parent CAS No. | 1956324-49-4 |
|---|---|
| Chemical Name | 5-(2-(Dimethylamino)ethoxy)-2-nitrophenyl dimethylcarbamate hydrochloride |
| SMILES | C1(OCCN(C)C)C=C(OC(=O)N(C)C)C([N+]([O-])=O)=CC=1.Cl |
| MFCD | N.A. |
| InChi | InChI=1S/C13H19N3O5.ClH/c1-14(2)7-8-20-10-5-6-11(16(18)19)12(9-10)21-13(17)15(3)4;/h5-6,9H,7-8H2,1-4H3;1H |
| InChiKey | TXUZOHBBKMDGRG-UHFFFAOYSA-N |
| CID | 145874871 |
| Short Description | PD-1 inhibitor |
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