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BAY-678

Axon 2822
CAS:  675103-36-3
  • Optical Purity:  99% e.e.
  • Soluble in DMSO
  • MF:  C20H15F3N4O2
  • MW:  400.35

Description

BAY-678 is a potent, selective and orally active human neutrophil elastase (HNE) inhibitor (IC50 value of 20 nM).

More Information

Parent CAS No. 675103-36-3
Chemical Name (R)-5-(5-Acetyl-6-methyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydropyrimidin-4-yl)picolinonitrile
SMILES CC(=O)C1=C(N(C(=O)N[C@@H]1C1C=NC(C#N)=CC=1)C1C=CC=C(C(F)(F)F)C=1)C |&1:9,r|
MFCD N.A.
InChi InChI=1S/C20H15F3N4O2/c1-11-17(12(2)28)18(13-6-7-15(9-24)25-10-13)26-19(29)27(11)16-5-3-4-14(8-16)20(21,22)23/h3-8,10,18H,1-2H3,(H,26,29)/t18-/m1/s1
InChiKey PGIVGIFOWOVINL-GOSISDBHSA-N
CID 23728722
Short Description HNE inhibitor

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