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STF 31
Axon 1905
CAS:
724741-75-7
Purity:
99%
- Soluble in DMSO
- MF: C23H25N3O3S
- MW: 423.53
Description
STF 31 is an inhibitor of glucose transporter 1 (GLUT1/SLC2A1) that blocks glucose uptake and targets metabolic dependency in susceptible cancer models.
GLUT1-mediated glucose transport supports glycolysis and survival in metabolically adapted tumor cells, including models with altered VHL/HIF signaling. STF 31 is used to study glucose-transport dependence and cancer metabolic vulnerability.
Key Features
- GLUT1/SLC2A1 inhibitor
- Blocks cellular glucose uptake
- Targets glycolytic dependency in susceptible tumor models
- Relevant to VHL/HIF-linked metabolic research
Applications
- GLUT1 transport assays
- Cancer metabolism and glycolysis studies
- VHL-deficient tumor model research
- Metabolic vulnerability and cell-viability assays
More Information
| Parent CAS No. | 724741-75-7 |
|---|---|
| Chemical Name | 4-((4-tert-butylphenylsulfonamido)methyl)-N-(pyridin-3-yl)benzamide |
| SMILES | C(NC1=CC=CN=C1)(=O)C1=CC=C(CNS(C2=CC=C(C(C)(C)C)C=C2)(=O)=O)C=C1 |
| MFCD | N.A. |
| InChi | InChI=1S/C23H25N3O3S/c1-23(2,3)19-10-12-21(13-11-19)30(28,29)25-15-17-6-8-18(9-7-17)22(27)26-20-5-4-14-24-16-20/h4-14,16,25H,15H2,1-3H3,(H,26,27) |
| InChiKey | NGQPRVWTFNBUHA-UHFFFAOYSA-N |
| CID | 984333 |
| Short Description | GLUT1 inhibitor |
STF 31
GLUT1/SLC2A1 inhibitor
STF31
GLUT1
SLC2A1
GLUT1/SLC2A1
Inhibitor
GLUT1 transport assays
Cancer metabolism and glycolysis studies
VHL-deficient tumor model research
Metabolic vulnerability and cell-viability assays
cancer biology
metabolism
transporter pharmacology
signal transduction
enzyme pharmacology
drug discovery
CAS 724741-75-7
Axon Medchem
Axon 1905
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