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SB 747651A

 - SB 747651 tetrahydrochloride
Axon 1897
  • Parent CAS:  607372-46-3
Purity:  98%
  • Soluble in water and DMSO
  • MF:  C16H22N8O.4HCl
  • MW:  488.24

Description

Potent MSK inhibitor; In vitro, SB-747651A inhibits MSK1 with an IC50 value of 11 nM; In cells, SB-747651A fully inhibited MSK activity at 5-10 μM.SB-747651A exhibited improved selectivity over H89 and Ro 31-8220 and therefore represents a useful tool to study MSK function in cells

More Information

Certificate of Analysis (B2)
Material Safety Data Sheet (B2)

Certificate of Analysis

B1

Material Safety Data Sheet

B1
Parent CAS No. 607372-46-3
Chemical Name 4-(1-ethyl-7-((piperidin-4-ylamino)methyl)-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine tetrahydrochloride
SMILES C1=NC=C(CNC2CCNCC2)C2N(CC)C(C3C(N)=NON=3)=NC1=2.Cl.Cl.Cl.Cl
MFCD N.A.
InChi InChI=1S/C16H22N8O.4ClH/c1-2-24-14-10(8-20-11-3-5-18-6-4-11)7-19-9-12(14)21-16(24)13-15(17)23-25-22-13;;;;/h7,9,11,18,20H,2-6,8H2,1H3,(H2,17,23);4*1H
InChiKey JBYSIGKTZDYOGF-UHFFFAOYSA-N
CID 91826488
Short Description MSK1 inhibitor

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