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Piboserod hydrochloride
- SB 207266A
Axon 1098
- Parent CAS: 152811-62-6
Purity:
99%
- Soluble in water
- MF: C22H31N3O2.HCl
- MW: 405.96
Description
Piboserod hydrochloride (SB 207266A) is a selective 5-HT4 receptor antagonist. It is used to investigate 5-HT4 receptor-mediated serotonergic signaling, especially in systems linked to gastrointestinal motility and CNS function.
The 5-HT4 receptor is a Gs-coupled serotonin receptor that regulates cAMP signaling, acetylcholine release and gastrointestinal contractility. Piboserod hydrochloride provides a tool for blocking 5-HT4 receptor responses in functional assays.
Key Features
- Selective 5-HT4 receptor antagonist
- Blocks 5-HT4-mediated GPCR signaling
- Useful for gastrointestinal and CNS serotonin pathway studies
- Blocks serotonin 5-HT4 receptor signaling
Applications
- 5-HT4 receptor pharmacology
- Serotonin GPCR antagonist assays
- Gastrointestinal motility research
- cAMP signaling studies
More Information
| Parent CAS No. | 152811-62-6 |
|---|---|
| Chemical Name | 3,4-Dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxylic acid (1-butyl-piperidin-4-ylmethyl)-amide hydrochloride |
| SMILES | C1(C(=O)NCC2CCN(CCCC)CC2)C2C=CC=CC=2N2CCCOC=12.Cl |
| MFCD | MFCD00943925 |
| InChi | InChI=1S/C22H31N3O2.ClH/c1-2-3-11-24-13-9-17(10-14-24)16-23-21(26)20-18-7-4-5-8-19(18)25-12-6-15-27-22(20)25;/h4-5,7-8,17H,2-3,6,9-16H2,1H3,(H,23,26);1H |
| InChiKey | UABVCZHWRUGYSR-UHFFFAOYSA-N |
| CID | 177335 |
| Short Description | 5-HT4 antagonist |
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