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p-MPPI
- Soluble in water
- MF: C25H27IN4O2
- MW: 542.41
Description
More Information
| Parent CAS No. | 155204-23-2 |
|---|---|
| Chemical Name | 4-Iodo-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-N-pyridin-2-yl-benzamide |
| SMILES | C1C=CC(OC)=C(N2CCN(CCN(C(C3=CC=C(I)C=C3)=O)C3N=CC=CC=3)CC2)C=1 |
| MFCD | MFCD00467897 |
| InChi | InChI=1S/C25H27IN4O2/c1-32-23-7-3-2-6-22(23)29-17-14-28(15-18-29)16-19-30(24-8-4-5-13-27-24)25(31)20-9-11-21(26)12-10-20/h2-13H,14-19H2,1H3 |
| InChiKey | DHMLNZRDVQLQBB-UHFFFAOYSA-N |
| CID | 4658 |
| Short Description | 5-HT1A antagonist |
References
- Thielen et al. 4-(2′-Methoxyphenyl)-1-[2′-[N-(2′′-pyridinyl)-p-iodo-benzamido]ethyl]piperazine and p-fluorobenzamido]ethyl]piperazine, two new antagonists at pre- and postsynaptic serotonin-1A receptors. J. Pharmacol. Exp. Ther. 1996, 277, 661.
- Kung et al. 4-(Methoxyphenyl)-1-[2′-(n-2″-pyridinyl)-p-iodobenzamido]-ethyl-piperazine ([125I]p-MPPI) as a new selective radioligand of serotonin-1A sites in rat brain. J. Pharmacol. Exp. Ther. 1995, 272, 429-437.
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