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PF-562271

Name: PF-562271
SKU: 4215

- VS6062

Axon 4215

CAS: 717907-75-0

Purity: 98%

Soluble in DMSO

MF: C21H20F3N7O3S
MW: 507.49

Description

PF-562271 is a potent, selective, ATP-competitive and reversible inhibitor of FAK and PYK2 catalytic activity with IC50 values of 1.5 and 14 nM, respectively.

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Certificate of Analysis (B1)

Material Safety Data Sheet (B1)

Parent CAS No.	717907-75-0
Chemical Name	N-Methyl-N-(3-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)pyridin-2-yl)methanesulfonamide
MFCD	MFCD16038299
Short Description	FAK/PYK2 inhibitor

PF-562271 FAK/PYK2 inhibitor VS6062 PF562271 PF 562271 VS 6062 VS-6062 PF-562 271 CAS 717907-75-0 Axon Medchem Axon 4215 MAPK FAK PYK2 Inhibitor Enzymes Supplier Vendor

References

WG Roberts et al. Antitumor activity and pharmacology of a selective focal adhesion kinase inhibitor, PF-562,271. Cancer Res. 2008 Mar 15;68(6):1935-44.

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PF-562271

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