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Axon 3898
CAS [1507370-20-8]
MF C26H26N4MW 394.51
BC-1215 is a selective and reversible Fbxo3 inhibitor. BC-1215 reduced TRAF protein levels, which potently inhibited cytokine release from human blood mononuclear cells. BC-1215 effectively lessened the severity of viral pneumonia, septic shock, colitis, and cytokine-driven inflammation systemically in murine models.
KEYWORDS: BC-1215 | Supplier | Fbxo3 inhibitor | BC1215 | BC 1215 | CAS [1507370-20-8] | [1507370-44-6] | Non Selective (Ubiquitin peptides) | Ubiquitin Ligase (E3; other) | Inhibitor | Enzymes | TNFR-associated factor | TRAF | Immunity | Skp-Cullin1-F box | SCF
N1,N2-Bis(4-(pyridin-2-yl)benzyl)ethane-1,2-diamine
[1507370-20-8]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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