BC-1215

Based on 7 reference(s) in Google Scholar 8 10 7

Axon 3898

CAS [1507370-20-8]

MF C26H26N4
MW 394.51

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO

BC-1215

Description

BC-1215 is a selective and reversible Fbxo3 inhibitor. BC-1215 reduced TRAF protein levels, which potently inhibited cytokine release from human blood mononuclear cells. BC-1215 effectively lessened the severity of viral pneumonia, septic shock, colitis, and cytokine-driven inflammation systemically in murine models.

KEYWORDS: BC-1215 | Supplier | Fbxo3 inhibitor | BC1215 | BC 1215 | CAS [1507370-20-8] | [1507370-44-6] | Non Selective (Ubiquitin peptides) | Ubiquitin Ligase (E3; other) | Inhibitor | Enzymes | TNFR-associated factor | TRAF | Immunity | Skp-Cullin1-F box | SCF

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Size Unit Price Stock
10 mg €99.00 In Stock
50 mg €330.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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