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(R)-(-)-Dimethindene maleate
- Parent CAS: 135821-89-5
- Optical Purity: 99.1% e.e.
- Soluble in water, DMSO and EtOH
- MF: C20H24N2.C4H4O4
- MW: 408.49
Description
More Information
| Parent CAS No. | 135821-89-5 |
|---|---|
| Chemical Name | (R)-N,N-Dimethyl-2-(3-(1-(pyridin-2-yl)ethyl)-1H-inden-2-yl)ethanamine maleate |
| SMILES | C1C=C2CC(CCN(C)C)=C([C@H](C3C=CC=CN=3)C)C2=CC=1.C(/C(=O)O)=C/C(=O)O |&1:11,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C20H24N2.C4H4O4/c1-15(19-10-6-7-12-21-19)20-17(11-13-22(2)3)14-16-8-4-5-9-18(16)20;5-3(6)1-2-4(7)8/h4-10,12,15H,11,13-14H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t15-;/m0./s1 |
| InChiKey | SWECWXGUJQLXJF-DASCVMRKSA-N |
| CID | 76955964 |
| Short Description | H1 antagonist |
References
- O Pfaff et al. The (S)-(+)-enantiomer of dimethindene: a novel M2-selective muscarinic receptor antagonist. Eur J Pharmacol. 1995 Nov 24;286(3):229-40.
- AM Ter Laak et al. Is there a difference in the affinity of histamine H1 receptor antagonists for CNS and peripheral receptors? An in vitro study. Eur J Pharmacol. 1993 Mar 2;232(2-3):199-205.
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