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BAY-091

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 3778

CAS [N.A.]

MF C26H21FN4O2
MW 440.47

Purity: 98%
Optical purity: 98.5% e.e.
Soluble in DMSO and EtOH

BAY-091

Description

BAY-091 is a potent and highly selective PIP4K2A inhibitor with an IC50 value of 16 nM (high ATP PIP4K2A HTRF assay).

The hydrochloride salt form, (Axon 3598) is also available.

KEYWORDS: BAY-091 | Supplier | PIP4K2A inhibitor | BAY091 | BAY 091 | CAS [N.A.] | Phosphatidylinositol | PIP4K | Inhibitor | Enzymes | Chemical probe

L Wortmann et al. Discovery and Characterization of the Potent and Highly Selective 1,7-Naphthyridine-Based Inhibitors BAY-091 and BAY-297 of the Kinase PIP4K2A. J Med Chem. 2021 Nov 11;64(21):15883-15911.

Apoptosis Cell Signaling & Oncology p53-Tumor Suppression EC 2.7.1.149

First potent and highly selective PIP4K2A inhibitor

Chemical name

(R)-2-(3-Cyano-2-(2'-fluoro-3'-methylbiphenyl-4-yl)-1,7-naphthyridin-4-ylamino)butanoic acid

Parent CAS No.

[N.A.]

Order

Size	Unit Price	Stock
5 mg	€130.00	In Stock
25 mg	€520.00	In Stock

Need more? Bulk Inquiry

Related Products

Axon ID	Name	Description	From price
3598	BAY-091 hydrochloride	First potent and highly selective PIP4K2A inhibitor		€130.00

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