Order

Size
Price
Stock
Qty

LockdownPro

Axon 3680
CAS:  2985814-80-8
Purity:  98%
  • Soluble in DMSO and EtOH
  • MF:  C39H40O10
  • MW:  668.73

Description

LockdownPro is an ester-modified variant of Lockdown, which is a potent, selective, cell-active, reversible, and non-competitive PPM1F inhibitor. LockdownPro displayed increased membrane permeability and prodrug-like properties. Importantly, LockdownPro efficiently suppressed tissue invasion of PPM1F-overexpressing human cancer cells in the chicken chorioallantoic membrane tumor assay.

More Information

Parent CAS No. 2985814-80-8
Chemical Name Tetraethyl 4,4'-(4,4'-(propane-2,2-diyl)bis(4,1-phenylene))bis(oxy)diphthalate
SMILES C1(C(OCC)=O)C=CC(OC2C=CC(C(C)(C)C3C=CC(OC4C=CC(C(=O)OCC)=C(C(=O)OCC)C=4)=CC=3)=CC=2)=CC=1C(OCC)=O
MFCD N.A.
InChi InChI=1S/C39H40O10/c1-7-44-35(40)31-21-19-29(23-33(31)37(42)46-9-3)48-27-15-11-25(12-16-27)39(5,6)26-13-17-28(18-14-26)49-30-20-22-32(36(41)45-8-2)34(24-30)38(43)47-10-4/h11-24H,7-10H2,1-6H3
InChiKey ROEOSYBNNXMANC-UHFFFAOYSA-N
CID 165436120
Short Description PPM1F inhibitor

Related Products

AXON ID NAME FROM PRICE
1821 CCT 007093

From $104.50

Other Categories

More Categories

Axon Ligands™ for Cell Signaling & Oncology

Axon Ligand™ for Stem Cell Research 

Axon Ligands™ for Epigenetic Research 

Loading...