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Ena21 hydrochloride
Axon 3674
- Parent CAS: 355816-26-1
Purity:
99%
- Soluble in water and DMSO
- MF: C18H21NO4.HCl
- MW: 351.82
Description
Ena21 hydrochloride is a selective and competitive inhibitor of ALKBH5 with an IC50 value of 15.7 μM. Ena21 had little inhibitory activity for fat mass and obesity-associated protein (FTO), which is another N6-methyladenosine demethylation enzyme.
More Information
| Parent CAS No. | 355816-26-1 |
|---|---|
| Chemical Name | N-((7-Methoxybenzo[d][1,3]dioxol-5-yl)methyl)-2-(4-methoxyphenyl)ethanamine hydrochloride |
| SMILES | C1(OC)C=CC(CCNCC2C=C3OCOC3=C(OC)C=2)=CC=1.Cl |
| MFCD | N.A. |
| InChi | InChI=1S/C18H21NO4.ClH/c1-20-15-5-3-13(4-6-15)7-8-19-11-14-9-16(21-2)18-17(10-14)22-12-23-18;/h3-6,9-10,19H,7-8,11-12H2,1-2H3;1H |
| InChiKey | NEJXVRSTWVQVNZ-UHFFFAOYSA-N |
| CID | 165436119 |
| Short Description | ALKBH5 inhibitor |
Ena21 hydrochloride
ALKBH5 inhibitor
Ena 21
Ena-21
CAS N.A.
CAS 355816-26-1
CAS 1046803-57-9
Axon Medchem
Axon 3674
DNA-RNA
Histone demethylase
Inhibitor
Enzymes
Glioblastoma multiforme
Alpha-ketoglutarate-dependent dioxygenase B (AlkB) homolog 5
N6-methyladenosine (m6 A) demethylation enzyme
alkB homolog 5
RNA demethylase
Supplier
Vendor
