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AKOS-022 - AKOS022075291

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 3524

CAS [878983-38-1]

MF C22H21ClF3N3O3
MW 467.87

Purity: 99%
Soluble in DMSO

AKOS-022

Description

AKOS-022 is a voltage-dependent anion channel 1 (VDAC1) inhibitor. AKOS-022 was found to inhibit VDAC1 oligomerization and apoptosis.

Keywords: AKOS-022 | Supplier | VDAC1 inhibitor | AKOS022075291 | AKOS022 | AKOS 022 | AKOS 022075291 | AKOS-022075291 | CAS [878983-38-1] | Non Selective (Anions) | VDAC | Inhibitor | Ion Channels | Parkinson's disease | Alzheimer's disease | Cardiovascular disease | Apoptosis

D Ben-Hail et al. Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction. J Biol Chem. 2016 Nov 25;291(48):24986-25003.

Apoptosis Cardiovascular CNS VDAC MAPK Unclassified

VDAC1 inhibitor

Chemical name

1-(4-Chlorophenyl)-3-(4-(4-(trifluoromethoxy)phenylamino)piperidin-1-yl)pyrrolidine-2,5-dione

Parent CAS No.

[878983-38-1]

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Size	Unit Price	Stock
10 mg	€120.00	In Stock
50 mg	€460.00	In Stock

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