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VU6005649
Axon 3487
CAS:
2137047-43-7
Purity:
99%
- Soluble in DMSO and EtOH
- MF: C16H12F5N3O
- MW: 357.28
Description
VU6005649 is a brain penetrant mGlu 7/8 receptor PAM with EC50 values of 649 nM and 2.6 μM for mGluR7 and mGluR8, respectively.
More Information
| Parent CAS No. | 2137047-43-7 |
|---|---|
| Chemical Name | 3-(2,3-Difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine |
| SMILES | C1=C(C(F)(F)F)N2N=C(C)C(C3C(F)=C(F)C(OC)=CC=3)=C2N=C1C |
| MFCD | N.A. |
| InChi | InChI=1S/C16H12F5N3O/c1-7-6-11(16(19,20)21)24-15(22-7)12(8(2)23-24)9-4-5-10(25-3)14(18)13(9)17/h4-6H,1-3H3 |
| InChiKey | NYBZCKAQIIPSDS-UHFFFAOYSA-N |
| CID | 131954513 |
| Short Description | mGluR7/8 PAM |
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