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Vardenafil dihydrochloride
- BAY 38–9456
Axon 3396
- Parent CAS: 224785-90-4
Purity:
99%
- Soluble in water and DMSO
- MF: C23H34Cl2N6O4S
- MW: 561.52
Description
Vardenafil dihydrochloride is a highly potent, selective and orally bioavailable cGMP phosphodiesterase (PDE5) inhibitor with IC50 values of 180 nM and 0.7 nM for PDE1 and PDE5, respectively.
More Information
| Parent CAS No. | 224785-90-4 |
|---|---|
| Chemical Name | 2-(2-Ethoxy-5-(4-ethylpiperazin-1-ylsulfonyl)phenyl)-5-methyl-7-propylimidazo[1,5-f][1,2,4]triazin-4(3H)-one dihydrochloride |
| SMILES | C1C(OCC)=C(C2NC(=O)C3=C(C)N=C(CCC)N3N=2)C=C(S(=O)(=O)N2CCN(CC)CC2)C=1.Cl.Cl |
| MFCD | MFCD07369690 |
| InChi | InChI=1S/C23H32N6O4S.2ClH/c1-5-8-20-24-16(4)21-23(30)25-22(26-29(20)21)18-15-17(9-10-19(18)33-7-3)34(31,32)28-13-11-27(6-2)12-14-28;;/h9-10,15H,5-8,11-14H2,1-4H3,(H,25,26,30);2*1H |
| InChiKey | NOIHTGOGFDFCBN-UHFFFAOYSA-N |
| CID | 135414253 |
| Short Description | PDE5 inhibitor |
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