Verteporfin - Visudyne

Based on 1987 reference(s) in Google Scholar 8 10 1987

Axon 3354

CAS [129497-78-5]

MF C41H42N4O8
MW 718.79

  • Purity: 99%
  • Soluble in DMSO

Verteporfin

Description

Verteporfin is an inhibitor of TEAD–YAP association and YAP-induced liver overgrowth. Moreover, Verteporfin treatment inhibited gastric carcinomas tumor growth in vivo. Also, Verteporfin is used clinically as a photosensitizer in photodynamic therapy for neovascular macular degeneration, where it is activated by a special wavelength laser light to generate reactive oxygen radicals that eliminate the abnormal blood vessels.

KEYWORDS: Verteporfin | YAP inhibitor | Visudyne | CAS [129497-78-5] | Hippo signaling pathway | YAP | Inhibitor | Transcription Factors | TAZ | YAP1 | TEAD

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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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