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BO-264
- Soluble in 0.1N HCl(aq) and DMSO
- MF: C18H19N5O3
- MW: 353.38
Description
BO-264 is a highly potent, orally active TACC3 inhibitor with an IC50 value of 188 nM. BO-264 is a potential anti-cancer agent, inducing spindle abnormalities and mitotic cell death.
More Information
| Parent CAS No. | 2408648-20-2 |
|---|---|
| Chemical Name | 3-(4-Methoxyphenyl)-N-(2-morpholinopyrimidin-4-yl)isoxazol-5-amine |
| SMILES | C1C=NC(N2CCOCC2)=NC=1NC1=CC(C2C=CC(OC)=CC=2)=NO1 |
| MFCD | N.A. |
| InChi | InChI=1S/C18H19N5O3/c1-24-14-4-2-13(3-5-14)15-12-17(26-22-15)20-16-6-7-19-18(21-16)23-8-10-25-11-9-23/h2-7,12H,8-11H2,1H3,(H,19,20,21) |
| InChiKey | WRCGBYNVBFVRTN-UHFFFAOYSA-N |
| CID | 146018837 |
| Short Description | TACC3 inhibitor |
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