Anastrozole - Arimidex | ZD1033 | ICI D1033

Based on 2886 reference(s) in Google Scholar 8 10 2886

Axon 3316

CAS [120511-73-1]

MF C17H19N5
MW 293.37

Purity: 99%
Soluble in DMSO

Anastrozole

Description

Anastrozole is a potent, highly selective, and orally active fourth-generation aromatase inhibitor (IC50 value of 15 nM) with no intrinsic hormonal activities.

PV Plourde et al. Arimidex: a potent and selective fourth-generation aromatase inhibitor. Breast Cancer Res Treat. 1994;30(1):103-11.

M Dukes et al. The preclinical pharmacology of "Arimidex" (anastrozole; ZD1033)--a potent, selective aromatase inhibitor. J Steroid Biochem Mol Biol. 1996 Jul;58(4):439-45.

Potent, highly selective, and orally active aromatase inhibitor

Chemical name

2,2'-(5-((1H-1,2,4-Triazol-1-yl)methyl)-1,3-phenylene)bis(2-methylpropanenitrile)

Parent CAS No.

[120511-73-1]

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Anastrozole - Arimidex | ZD1033 | ICI D1033

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