Tedizolid phosphate - TR701 | Torezolid phosphate | DA7218

Based on 188 reference(s) in Google Scholar 8 10 188

Axon 3312

CAS [856867-55-5]

MF C17H16FN6O6P
MW 450.32

Purity: 99%
Optical purity: Optically pure
Soluble in 0.1N NaOH(aq) and DMSO

Tedizolid phosphate

Description

Tedizolid phosphate is an oxazolidinone prodrug of Tedizolid, which is a highly potent antibacterial agent displaying good activity against important Gram-positive pathogens, particularly methicillin-resistant Staphylococcus aureus (MRSA) and some linezolid-resistant staphylococci.

KEYWORDS: Tedizolid phosphate | Antibiotic | TR701 | Torezolid phosphate | DA7218 | TR 701 | TR-701 | DA 7218 | DA-7218 | CAS [856867-55-5] | [856867-39-5] | DNA-RNA | Peptidyl Transferase | Inhibitor | Enzymes | Prodrug

WB Im et al. Discovery of torezolid as a novel 5-hydroxymethyl-oxazolidinone antibacterial agent. Eur J Med Chem. 2011 Apr;46(4):1027-39.

SD Brown et al. Comparative in vitro antimicrobial activities of torezolid (TR-700),xxx, determination of tentative disk diffusion interpretive criteria, and quality control ranges. Antimicrob Agents Chemother. 2010 May;54(5):2063-9.

C Foti et al. Oxazolidinone Antibiotics: Chemical, Biological and Analytical Aspects. Molecules. 2021 Jul 14;26(14):4280.

Protein synthesis inhibitor; antibiotic

Chemical name

(R)-(3-(3-Fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-2-oxooxazolidin-5-yl)methyl dihydrogen phosphate

Parent CAS No.

[856867-55-5]

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Tedizolid phosphate - TR701 | Torezolid phosphate | DA7218

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Tedizolid phosphate - TR701 | Torezolid phosphate | DA7218

Description

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Parent CAS No.

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