MYCi975 - NUCC-0200975

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 3229

CAS [2289691-01-4]

MF C25H16Cl2F6N2O2
MW 561.30

  • Purity: 99%
  • Soluble in DMSO



MYCi975 is a MYC inhibitor which disrupts MYC/MAX interaction while also decreasing MYC protein stability. This dual mechanism of action leads to significant inhibition of MYC-dependent cancer-cell proliferation in vitro with suppression of global MYC target gene expression and inhibition of tumor growth in vivo. Moreover, MYCi975 showed an excellent pharmacokinetic profile, with a long terminal half-life, high peak plasma concentration, and tumor penetration, as demonstrated by pharmacodynamic markers, such as MYC T58 phosphorylation. MYCi975 enhanced immunotherapy.

KEYWORDS: MYCi975 | supplier | MYC inhibitor | NUCC-0200975 | NUCC 0200975 | NUCC0200975 | CAS [2289691-01-4] | DNA-RNA | c-MYC | Inhibitor | Transcription Factors

Size Unit Price Stock
5 mg €120.00 In Stock
25 mg €400.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €200.00 In Stock
2 x 25 mg €720.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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