Based on 20 reference(s) in Google Scholar 80 100 20

Axon 3108

CAS [695207-56-8]

MF C22H27N3O4S
MW 429.53

  • Purity: 99%
  • Soluble in DMSO



BC-LI-0186 is a specific inhibitor of the interaction between Leucyl-tRNA synthetase (LRS) and RagD (IC50 of 46.11 nM). BC-LI-0186 bound to LRS with a Kd value of 42.1 nM. BC-LI-0186 efficiently inhibited leucine-dependent mTORC1 activity and the growth of cancer cells that express drug-resistant MTOR mutations.

KEYWORDS: BC-LI-0186 | supplier | LRS-RagD inhibitor | BC-LI0186 | BC-LI 0186 | CAS [695207-56-8] | DNA-RNA | LRS | Inhibitor | Enzymes

Size Unit Price Stock
10 mg €90.00 In Stock
50 mg €360.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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