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Axon 3108
CAS [695207-56-8]
MF C22H27N3O4SMW 429.53
BC-LI-0186 is a specific inhibitor of the interaction between Leucyl-tRNA synthetase (LRS) and RagD (IC50 of 46.11 nM). BC-LI-0186 bound to LRS with a Kd value of 42.1 nM. BC-LI-0186 efficiently inhibited leucine-dependent mTORC1 activity and the growth of cancer cells that express drug-resistant MTOR mutations.
KEYWORDS: BC-LI-0186 | supplier | LRS-RagD inhibitor | BC-LI0186 | BC-LI 0186 | CAS [695207-56-8] | DNA-RNA | LRS | Inhibitor | Enzymes
4-(4-Isopropyl-2,3-dimethyl-5-oxo-2,5-dihydro-1H-pyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide
[695207-56-8]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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