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Verinurad
Axon 2938
CAS:
1352792-74-5
Purity:
98%
- Soluble in 0.1N NaOH(aq) and DMSO
- MF: C20H16N2O2S
- MW: 348.42
Description
Verinurad is a highly potent and specific URAT1 inhibitor (IC50 value of 25 nM) with greater than 100-fold potency for URAT1 compared to other transporters. Under evaluation for the treatment of gout and asymptomatic hyperuricemia.
More Information
| Parent CAS No. | 1352792-74-5 |
|---|---|
| Chemical Name | 2-(3-(4-Cyanonaphthalen-1-yl)pyridin-4-ylthio)-2-methylpropanoic acid |
| SMILES | C1C(C2C=NC=CC=2SC(C)(C)C(=O)O)=C2C=CC=CC2=C(C#N)C=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C20H16N2O2S/c1-20(2,19(23)24)25-18-9-10-22-12-17(18)16-8-7-13(11-21)14-5-3-4-6-15(14)16/h3-10,12H,1-2H3,(H,23,24) |
| InChiKey | YYBOLPLTQDKXPM-UHFFFAOYSA-N |
| CID | 54767229 |
| Short Description | URAT1 inhibitor |
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