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PF 04859989 hydrochloride
- L-3-Amino-3,4-dihydro-1-hydroxycarbstyril hydrochloride
Axon 2924
- Parent CAS: 34783-48-7
- Optical Purity: Optically pure
- Soluble in water and DMSO
- MF: C9H10N2O2.HCl
- MW: 214.65
Description
PF 04859989 hydrochloride is a potent, selective, brain-penetrant, irreversible kynurenine aminotransferase II (KAT II) inhibitor with an IC50 value of 23 nM.
More Information
| Parent CAS No. | 34783-48-7 |
|---|---|
| Chemical Name | (S)-3-Amino-1-hydroxy-3,4-dihydroquinolin-2(1H)-one hydrochloride |
| SMILES | C1C=C2N(O)C(=O)[C@@H](N)CC2=CC=1.Cl |&1:7,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C9H10N2O2.ClH/c10-7-5-6-3-1-2-4-8(6)11(13)9(7)12;/h1-4,7,13H,5,10H2;1H/t7-;/m0./s1 |
| InChiKey | WZOBDOKCHIUXAY-FJXQXJEOSA-N |
| CID | 22868922 |
| Short Description | KAT II inhibitor |
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