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Lomitapide - BMS 201038 | AEGR-733

Based on 177 reference(s) in Google Scholar 8 10 177

Axon 2917

CAS [182431-12-5]

MF C39H37F6N3O2
MW 693.72

  • Purity: 98%
  • Soluble in DMSO

Lomitapide

Description

Lomitapide is a highly potent microsomal triglyceride transfer protein (MTP) inhibitor with an IC50 value of 0.5 nM. Moreover, lomitapide inhibited the production of lipoprotein particles in rodent models and normalized plasma lipoprotein levels in Watanabe-heritable hyperlipidemic (WHHL) rabbits, which are a model for human homozygous familial hypercholesterolemia.

KEYWORDS: Lomitapide | supplier | MTP inhibitor | BMS 201038 | AEGR-733 | BMS201038 | BMS-201038 | AEGR 733 | AEGR733 | CAS [182431-12-5] | CAS [202914-84-9] | CAS [182431-10-3] | Triglycerides | MTP | Inhibitor | Proteins | Hypercholesterolemia

Potent microsomal triglyceride transfer protein (MTP) inhibitor

Chemical name

N-(2,2,2-trifluoroethyl)-9-(4-(4-(4'-(trifluoromethyl)biphenyl-2-ylcarboxamido)piperidin-1-yl)butyl)-9H-fluorene-9-carboxamide

Parent CAS No.

[182431-12-5]

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10 mg €125.00 In Stock
50 mg €375.00 In Stock
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Related Products

Axon ID Name Description From price
2216 CP 346086 Potent microsomal triglyceride transfer protein (MTP) inhibitor €140.00

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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