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Exo1
- Soluble in DMSO
- MF: C15H12FNO3
- MW: 273.26
Description
Exo1 is a chemical inhibitor of the exocytic pathway with an IC50 value of 20 µM. Exo1 induces a rapid collapse of the Golgi to the endoplasmic reticulum, thus acutely inhibiting the traffic emanating from the endoplasmic reticulum. Moreover, Exo1 induces the rapid release of ADP-ribosylation factor (ARF) 1 from Golgi membranes but has less effect on the organization of the trans-Golgi network.
More Information
| Parent CAS No. | 75541-83-2 |
|---|---|
| Chemical Name | Methyl 2-(4-fluorobenzamido)benzoate |
| SMILES | C1C=C(C(NC2C=CC=CC=2C(OC)=O)=O)C=CC=1F |
| MFCD | MFCD00028104 |
| InChi | InChI=1S/C15H12FNO3/c1-20-15(19)12-4-2-3-5-13(12)17-14(18)10-6-8-11(16)9-7-10/h2-9H,1H3,(H,17,18) |
| InChiKey | KIAPWMKFHIKQOZ-UHFFFAOYSA-N |
| CID | 310557 |
| Short Description | Exocytic pathway inhibitor |
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