Based on 1 reference(s) in Google Scholar 8 10 1

Axon 2883

CAS [100750-39-8]

MF C14H13NO3
MW 243.26

  • Purity: 99%
  • Soluble in DMSO



APPA is an aldose reductase inhibitor with an IC50 value of 0.0223 μM. APPA could inhibit apoptosis in rat glomerular mesangial cells in vitro. In addition, APPA improved the pathological symptoms of streptozotocin-induced diabetic nephropathy (DN) in rats by affecting antioxidant activities and reducing the levels of TGF-β, collagen IV, and laminin.

KEYWORDS: APPA | supplier | Aldose reductase inhibitor | CAS [100750-39-8] | Aldose | Aldose reductase | Inhibitor | Enzymes | Diabetic Nephropathy | Diabetes Mellitus | Polyol Pathway

Size Unit Price Stock
10 mg €105.00 In Stock
50 mg €365.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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