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Motolimod - VTX-2337 | VTX-378

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 2783

CAS [926927-61-9]

MF C28H34N4O2
MW 458.60

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO

Motolimod

Description

Motolimod is a highly potent and selective TLR8 agonist (EC50 value of 100 nM). Motolimod directly activates myeloid dendritic cells, monocytes, and NK cells, resulting in the production of high levels of mediators including: TNFα, IL-12, and IFNγ, known to orchestrate adaptive antitumor responses.

KEYWORDS: Motolimod | supplier | TLR8 agonist  | VTX-2337 | VTX-378 | VTX 2337 | VTX2337 | VTX 378 | VTX378 | CAS [926927-61-9] | DNA-RNA | TLR8 | Agonist | Receptors | Antitumor

Highly potent and selective TLR8 agonist

Chemical name

(1E,4E)-2-Amino-N,N-dipropyl-8-(4-(pyrrolidine-1-carbonyl)phenyl)-3H-benzo[b]azepine-4-carboxamide

Parent CAS No.

[926927-61-9]

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5 mg €145.00 In Stock
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2 x 5 mg €230.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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