STK16-IN-1

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 2743

CAS [1223001-53-3]

MF C17H12FN3O
MW 293.30

  • Purity: 99%
  • Soluble in DMSO

STK16-IN-1

Description

STK16-IN-1 is a highly selective ATP-competitive inhibitor which exhibits potent inhibitory activity against STK16 kinase (IC50 value of 0.295 μM). In MCF-7 cells, treatment with STK16-IN-1 results in a reduction in cell number and accumulation of binucleated cells, which can be recapitulated by RNAi knockdown of STK16. Co-treatment of STK16-IN-1 with chemotherapeutics results in a slight potentiation of the antiproliferative effects of the chemotherapeutics.
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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