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Featured Products
Axon 2546
CAS [1527473-33-1]
MF C17H15N5OMW 305.33
Highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor (IC50 value 3 nM); an exceptional tool compound to study the function of LRRK2 PF 06447475 mitigates both neurodegeneration and neuroinflammation associated with G2019S-LRRK2 expression by LRRK2 kinase inhibition in rats.
KEYWORDS: PF 06447475 | supplier | LRRK2 inhibitor | PF06447475 | CAS [1527473-33-1] | LRRK2 | Inhibitor | neurodegeneration | neuroinflammation | Parkinson's |Huntington's | PD | dopamine | synuclein
3-(4-morpholino-7H-pyrrolo[2,3-d]pyrimidin-5-yl)benzonitrile
[1527473-33-1]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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