SCR7 pyrazine

Based on 31 publications in PubMed 9 10 31

Axon 2531

CAS [14892-97-8]

MW 332.38

  • Purity: 99%
  • Soluble in DMSO

SCR7 pyrazine


DNA ligase IV mediated inhibitor of NHEJ (non-homologous end joining) that increases the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells up to 19-fold.

Note: Axon Medchem confirmed that the active chemical entity of SCR7, as described by Srivastava and others, is actually SCR7 pyrazine (Axon 2531). Careful application of the synthetic conditions described in this paper and comparison with authentic SCR7 pyrazine reveals identical chemical products.

KEYWORDS: SCR7 pyrazine | supplier | NHEJ/DNA ligase IV inhibitor | CAS [14892-97-8] | [67648-82-2] | [1538566-74-3] | DNA-RNA | DNA ligase | Inhibitor | Non-homologous end joining | CRISPR | Cas9 | DSB | double strand breaks | DNA repair | tumor progression

Size Unit Price Stock
2 mg €65.00 In Stock
10 mg €125.00 In Stock
50 mg €450.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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