BMH 21

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 2462

CAS [896705-16-1]

MF C21H20N4O2
MW 360.41

  • Purity: 99%
  • Soluble in 0.1N HCl (aq)

BMH 21


RNA polymerase I (RNAP1) inhibitor (IC50 values 0.05 µM and 0.07 µM for degradation of RPA194 and translocation of NCL, respectively). BMH-21 intercalates with GC-rich rDNA, inhibits Pol I, and causes activation of p53 and proteasome-mediated degradation of RPA194. Furthermore, BMH21 showed broad and potent anticancer activity in NCI60 cancer cell lines and reduced tumor burden in mouse xenograft assays.
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10 mg €95.00 In Stock
50 mg €325.00 In Stock
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Size Unit Price Stock
2 x 10 mg €150.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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