FIPI hydrochloride

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2281

CAS [N.A.]

MF C23H24FN5O2.HCl
MW 457.93

  • Purity: 99%
  • Soluble in DMSO

FIPI hydrochloride

Description

Phospholipase D (PLD) inhibitor (IC50 values of 20-25 nM for both PLD1 and PLD2) that rapidly blocks in vivo phosphatidic acid (PA) production with subnanomolar potency. FIPI does inhibit PLD regulation of F-actin cytoskeleton reorganization, PIP2 availability, cell spreading, and chemotaxis, indicating potential utility for it as a therapeutic for autoimmunity and cancer metastasis.
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5 mg €100.00 In Stock
25 mg €360.00 In Stock
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2 x 5 mg €160.00 In Stock
2 x 25 mg €600.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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