ASK1 Inhibitor 10

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 2179

CAS [1005775-56-3]

MF C21H21N5O.2HCl
MW 432.35

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO

ASK1 Inhibitor 10


Potent, selective, and orally bioavailable ASK1 inhibitor (IC50: 14 nM) with no affinity for a representative panel of kinases (IC50: >10 μM), except for ASK2 (IC50: 0.51 μM). Compound 10 shows a high ligand-lipophilicity efficiency (LLE, pIC50–logD = 4.69) value, which avoids issues of undesirable physical properties and ADME (absorption, distribution, metabolism, and elimination) profiles and interactions with other protein kinases and adverse biological activities.
Size Unit Price Stock
10 mg €130.00 In Stock
50 mg €470.00 In Stock
Special Offers
Size Unit Price Stock
2 x 10 mg €220.00 In Stock
2 x 50 mg €800.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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