UNC 569

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 2086

CAS [1350547-65-7]

MF C22H29FN6
MW 396.50

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO

UNC 569

Description

Potent, reversible and ATP-competitive inhibitor of Mer receptor tyrosine kinase (RTK) (IC50: 2.9 nM). UNC 569 inhibits Mer activation and downstream signaling through ERK1/2 and AKT and was capable of inducing >50% reduction in tumor burden compared to references. Potential therapeutic for acute lymphoblastic leukemia (ALL) and atypical teratoid/rhabdoid tumors (ATRT).

KEYWORDS: UNC 569 | supplier | Mer Inhibitor | UNC569 | CAS [1350547-65-7] | Gas6 | Mer | Inhibitor | Receptors | RTK

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5 mg €95.00 In Stock
25 mg €380.00 In Stock
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2 x 5 mg €150.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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