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Enzymes
Hydrolases
Proteases (Amino-)
MetAP2
A 357300 hydrochloride

A 357300 hydrochloride

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1666

CAS [369358-07-6]

MF C15H22ClN3O3S.HCl
MW 396.33

Purity: 100%
Optical purity: Optically pure
Soluble in DMSO

A 357300 hydrochloride

Description

Potent and reversible inhibitor of methionine aminopeptidase-2 (MetAP-2)

J Wang et al. Tumor suppression by a rationally designed reversible inhibitor of methionine aminopeptidase-2. Cancer Res. 2003, 63(22), 7861-7869.

MJ Morowitz et al. Methionine aminopeptidase 2 inhibition is an effective treatment strategy for neuroblastoma in preclinical models. Clin. Cancer Res. 2005, 11(7), 2680-2685.

Angiogenesis Cardiovascular Cell Signaling & Oncology MetAP2 EC 3.4.11.18

MetAP2 inhibitor

Chemical name

N'-((2S,3R)-3-amino-2-hydroxy-5-(isopropylthio)pentanoyl)-3-chlorobenzohydrazide hydrochloride

Parent CAS No.

[369358-07-6]

Order

Size	Unit Price	Stock
5 mg	€90.00	In Stock
25 mg	€270.00	In Stock

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3208	ERAP1 inhibitor compound 3	Selective ERAP1 inhibitor		€160.00

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