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Remogliflozin
- GSK 189074
Axon 1634
CAS:
329045-45-6
Purity:
99%
- Soluble in water and DMSO
- MF: C23H34N2O7
- MW: 450.53
Description
Remogliflozin (GSK189074) is an inhibitor of sodium-glucose cotransporter 2 (SGLT2), the renal transporter responsible for much of filtered glucose reabsorption.
SGLT2 inhibition reduces renal glucose reuptake and promotes urinary glucose excretion, a mechanism relevant to metabolic disease pharmacology. Remogliflozin is useful for studying renal glucose transport, glycemic control pathways and SGLT2 selectivity.
Key Features
- SGLT2 sodium-glucose cotransporter inhibitor
- Blocks renal glucose reabsorption pathways
- Promotes glucosuria-related glucose lowering mechanisms
- Relevant to type 2 diabetes and renal transporter research
Applications
- SGLT2 transporter pharmacology
- Renal glucose handling assays
- Type 2 diabetes model studies
- Metabolic disease drug-discovery research
More Information
| Parent CAS No. | 329045-45-6 |
|---|---|
| Chemical Name | (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(4-(4-isopropoxybenzyl)-1-isopropyl-5-methyl-1H-pyrazol-3-yloxy)tetrahydro-2H-pyran-3,4,5-triol |
| MFCD | N.A. |
| Short Description | SGLT2 inhibitor |
Remogliflozin (GSK189074)
SGLT2 sodium-glucose cotransporter inhibitor
Remogliflozin
GSK189074
SGLT2
SGLT2 sodium-glucose cotransporter
Inhibitor
SGLT2 transporter pharmacology
Renal glucose handling assays
Type 2 diabetes model studies
Metabolic disease drug-discovery research
metabolism
diabetes research
transporter pharmacology
receptor selectivity
enzyme pharmacology
drug discovery
CAS 329045-45-6
Axon Medchem
Axon 1634
Supplier
Vendor
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