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AH 002
- 8-M-PDOT
Axon 1336
CAS:
134865-70-6
Purity:
98%
- Soluble in DMSO
- MF: C14H19NO2
- MW: 233.31
Description
AH 002 (8-M-PDOT) is a melatonin receptor agonist with greater selectivity for MT2 over MT1 compared with AH-001, although with lower potency.
Melatonin MT1 and MT2 receptors regulate circadian timing, sleep-wake biology and retinal/neuroendocrine signaling. AH 002 is useful for probing MT2-preferential melatonergic responses.
Key Features
- Melatonin receptor agonist
- MT2-selective profile relative to MT1
- Less potent than AH-001 but more MT2-selective
- Useful for circadian and sleep-wake pathway research
Applications
- MT2 receptor functional assays
- Melatonin receptor subtype profiling
- Circadian rhythm and chronobiology studies
- Sleep-wake signaling research
More Information
| Parent CAS No. | 134865-70-6 |
|---|---|
| Chemical Name | N-(8-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propionamide |
| SMILES | C1C(OC)=C2CC(NC(=O)CC)CCC2=CC=1 |
| MFCD | MFCD00901636 |
| InChi | InChI=1S/C14H19NO2/c1-3-14(16)15-11-8-7-10-5-4-6-13(17-2)12(10)9-11/h4-6,11H,3,7-9H2,1-2H3,(H,15,16) |
| InChiKey | RVIGBTUDFAGRTQ-UHFFFAOYSA-N |
| CID | 5170952 |
| Short Description | Melatonin agonist |
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