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Luzindole
- N 0774
Axon 1350
CAS:
117946-91-5
Purity:
99%
- Soluble in DMSO
- MF: C19H20N2O
- MW: 292.37
Description
A putative melatonin antagonist
More Information
| Parent CAS No. | 117946-91-5 |
|---|---|
| Chemical Name | N-[2-(2-Benzyl-1H-indol-3-yl)-ethyl]-acetamide |
| SMILES | C1C=C2NC(CC3C=CC=CC=3)=C(CCNC(C)=O)C2=CC=1 |
| MFCD | MFCD00672498 |
| InChi | InChI=1S/C19H20N2O/c1-14(22)20-12-11-17-16-9-5-6-10-18(16)21-19(17)13-15-7-3-2-4-8-15/h2-10,21H,11-13H2,1H3,(H,20,22) |
| InChiKey | WVVXBPKOIZGVNS-UHFFFAOYSA-N |
| CID | 122162 |
| Short Description | Melatonin antagonist |
References
- C Browning et al., Pharmacological characterization of human recombinant melatonin MT(1) and MT(2) receptors. Br. J. Pharmacol. 2000, 129, 877-886.
- ML Dubocovich. Luzindole (N-0774): a novel melatonin receptor antagonist. J. Pharmacol. Exp. Ther. 1988, 246, 902-910.
- M Zhou et al. Luzindole, a melatonin receptor antagonist, inhibits the transient outward K+ current in rat cerebellar granule cells. Brain Res. 2003, 970, 169-177.
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