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TEI 6720
- Febuxostat
Axon 1175
CAS:
144060-53-7
Purity:
99%
- Soluble in DMSO
- MF: C16H16N2O3S
- MW: 316.37
Description
A non-purine selective xanthine oxidase (XO) inhibitor
More Information
| Parent CAS No. | 144060-53-7 |
|---|---|
| Chemical Name | 2-(3-Cyano-4-isobutoxy-phenyl)-4-me thyl-thiazole-5-carboxylic acid |
| SMILES | C1C=C(OCC(C)C)C(C#N)=CC=1C1=NC(C)=C(C(O)=O)S1 |
| MFCD | MFCD00871598 |
| InChi | InChI=1S/C16H16N2O3S/c1-9(2)8-21-13-5-4-11(6-12(13)7-17)15-18-10(3)14(22-15)16(19)20/h4-6,9H,8H2,1-3H3,(H,19,20) |
| InChiKey | BQSJTQLCZDPROO-UHFFFAOYSA-N |
| CID | 134018 |
| Short Description | XO inhibitor |
References
- T Yamamoto et al. Effect of TEI-6720, a xanthine oxidase inhibitor, on the nucleoside transport in the lung cancer cell line A549. Pharmacology 2000, 60(1), 34-40.
- K Okamoto et al. An extremely potent inhibitor of xanthine oxidoreductase. Crystal structure of the enzyme-inhibitor complex and mechanism of inhibition. J. Biol. Chem. 2003, 278(3), 1848-1855.
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