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AKOS-022

Name: AKOS-022
SKU: 3524

- AKOS022075291

Axon 3524

CAS: 878983-38-1

Purity: 99%

Soluble in DMSO

MF: C22H21ClF3N3O3
MW: 467.87

Description

AKOS-022 is a voltage-dependent anion channel 1 (VDAC1) inhibitor. AKOS-022 was found to inhibit VDAC1 oligomerization and apoptosis.

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Certificate of Analysis (B1)

Material Safety Data Sheet (B1)

VDAC

Parent CAS No.	878983-38-1
Chemical Name	1-(4-Chlorophenyl)-3-(4-(4-(trifluoromethoxy)phenylamino)piperidin-1-yl)pyrrolidine-2,5-dione
MFCD	N.A.
Short Description	VDAC1 inhibitor

AKOS-022 VDAC1 inhibitor AKOS022075291 AKOS022 AKOS 022 AKOS 022075291 AKOS-022075291 CAS 878983-38-1 Axon Medchem Axon 3524 Non Selective (Anions) VDAC Inhibitor Ion Channels Parkinson's disease Alzheimer's disease Cardiovascular disease Apoptosis Supplier Vendor

References

D Ben-Hail et al. Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction. J Biol Chem. 2016 Nov 25;291(48):24986-25003.

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AKOS-022

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