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ISO-1

Name: ISO-1
SKU: 3949

Axon 3949

CAS: 478336-92-4

Purity: 99%

Soluble in DMSO and EtOH

MF: C12H13NO4
MW: 235.24

Description

ISO-1 is an inhibitor of the macrophage migration inhibitory factor (MIF) with an IC50 value of 7 μM for inhibition of MIF tautomerase activity.

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Certificate of Analysis (B1)

Material Safety Data Sheet (B1)

Parent CAS No.	478336-92-4
Chemical Name	Methyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetate
MFCD	MFCD22376813
Short Description	MIF inhibitor

ISO-1 MIF inhibitor ISO1 ISO 1 CAS 478336-92-4 Axon Medchem Axon 3949 p-Hydroxyphenyl-pyruvate (HPP);Phenylpyruvate MIF Inhibitor Receptors Inflammatory disease Innate immunity Supplier Vendor

References

JB Lubetsky et al. The tautomerase active site of macrophage migration inhibitory factor is a potential target for discovery of novel anti-inflammatory agents. J Biol Chem. 2002 Jul 12;277(28):24976-82.

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ISO-1

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