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MIF098
Axon 4342
CAS:
1208448-95-6
Purity:
99%
- Soluble in DMSO and EtOH
- MF: C15H13NO3
- MW: 255.27
Description
MIF098 is a MIF antagonist which blocks MIF binding to its cognate receptor CD74, suppressed NLRP3 upregulation, a rate-limiting step in activating the NLRP3 inflammasome, as well as caspase-1 activation and downstream interleukin (IL)-1β production in snRNP immune complex-stimulated human monocytes.
More Information
| Parent CAS No. | 1208448-95-6 |
|---|---|
| Chemical Name | 3-((3-Hydroxyphenyl)methyl)-5-methyl-1,3-benzoxazolidin-2(3H)-one |
| SMILES | C1=C2OC(=O)N(CC3=CC(O)=CC=C3)C2=CC(C)=C1 |
| MFCD | N.A. |
| InChi | InChI=1S/C15H13NO3/c1-10-5-6-14-13(7-10)16(15(18)19-14)9-11-3-2-4-12(17)8-11/h2-8,17H,9H2,1H3 |
| InChiKey | JJXKGUBHEQGADG-UHFFFAOYSA-N |
| CID | 44631884 |
| Short Description | MIF antagonist |
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