Bulk Inquiry
LEI-301
Axon 3296
CAS:
2571585-09-4
Purity:
99%
- Soluble in DMSO and EtOH
- MF: C25H25NO3
- MW: 387.47
Description
LEI-301 is a potent inhibitor for the PLAAT family members with pIC50 values of 7.3, 6.6, 7.3 and 7.4 for PLAAT2, PLAAT3, PLAAT4 and PLAAT5, respectively. LEI-301 was selective over the proteins of the endocannabinoid system (ECS). Moreover, LEI-301 reduced the NAE levels, including anandamide, in cells overexpressing PLAAT2 or PLAAT5.
More Information
| Parent CAS No. | 2571585-09-4 |
|---|---|
| Chemical Name | 2-Oxo-N-(4-phenoxyphenethyl)-5-phenylpentanamide |
| SMILES | C1C=CC(CCCC(=O)C(=O)NCCC2C=CC(OC3C=CC=CC=3)=CC=2)=CC=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C25H25NO3/c27-24(13-7-10-20-8-3-1-4-9-20)25(28)26-19-18-21-14-16-23(17-15-21)29-22-11-5-2-6-12-22/h1-6,8-9,11-12,14-17H,7,10,13,18-19H2,(H,26,28) |
| InChiKey | YWYSSOKJGYXYIM-UHFFFAOYSA-N |
| CID | 156018782 |
| Short Description | PLAAT inhibitor |
