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XAF-1407
Axon 3265
CAS:
2785323-66-0
Purity:
99%
- Soluble in 0.1N HCl(aq), DMSO and EtOH
- MF: C28H37N5O2S
- MW: 507.69
Description
XAF-1407 is a potent and highly selective inhibitor of the ion channels formed by Kir3.1/3.4 heterotetramers and Kir3.4 homotetramers that carry the IKACh current (IC50 values of 1.1 and 3.2 nM, respectively).
More Information
| Parent CAS No. | 2785323-66-0 |
|---|---|
| Chemical Name | 3-Methyl-1-(5-phenyl-4-(4-((2-(pyrrolidin-1-yl)ethoxy)methyl)piperidin-1-yl)thieno[2,3-d]pyrimidin-6-yl)azetidin-3-ol |
| SMILES | C1C(COCCN2CCCC2)CCN(C2N=CN=C3SC(N4CC(O)(C)C4)=C(C4C=CC=CC=4)C=23)C1 |
| MFCD | N.A. |
| InChi | InChI=1S/C28H37N5O2S/c1-28(34)18-33(19-28)27-23(22-7-3-2-4-8-22)24-25(29-20-30-26(24)36-27)32-13-9-21(10-14-32)17-35-16-15-31-11-5-6-12-31/h2-4,7-8,20-21,34H,5-6,9-19H2,1H3 |
| InChiKey | AVTFTJSBFXQTLR-UHFFFAOYSA-N |
| CID | 163342401 |
| Short Description | IKACh inhibitor |
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