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10 mg

$121.00

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CZL80

Name: CZL80
SKU: 4346

Axon 4346

CAS: 313482-91-6

Purity: 99%

Soluble in 0.1N NaOH(aq) and DMSO

MF: C19H14N2O4S
MW: 366.39

Description

CZL80 is a potent, selective, BBB penetrable and efficacious caspase-1 inhibitor with an IC50 value of 0.024 µM.

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Certificate of Analysis (B2)

Material Safety Data Sheet (B2)

Caspase

Parent CAS No.	313482-91-6
Chemical Name	3-(3-(2-Thenylamino)benzylamino)benzoic acid
MFCD	N.A.
Short Description	Caspase-1 inhibitor

CZL80 Caspase-1 inhibitor CZL-80 CZL 80 CAS 313482-91-6 Axon Medchem Axon 4346 Amyloids Caspase Inhibitor Enzymes Febrile seizures Epileptogenesis Anti-convulsant Supplier Vendor

References

Y Tang et al. Structure-based discovery of CZL80, a caspase-1 inhibitor with therapeutic potential for febrile seizures and later enhanced epileptogenic susceptibility. Br J Pharmacol. 2020 Aug;177(15):3519-3534.

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CZL80

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